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India has recently detected two new COVID-19 variants—NB.1.8.1 and LF.7—according to data from the Indian SARS-CoV-2 Genomics Consortium (INSACOG). These variants are part of the Omicron family and are currently being monitored due to their potential to spread or cause concern.
Where Have They Been Found?NB.1.8.1 was found in Tamil Nadu in April 2025.LF.7 has been reported in Gujarat, with 4 cases detected in May 2025.These variants are descendants of JN.1, which is the most dominant variant in India right now, accounting for over 50% of the cases being genetically sequenced.
The World Health Organization (WHO) has categorized both NB.1.8.1 and LF.7 as Variants Under Monitoring (VUM). This means that, while they aren’t considered high risk yet, they are being closely.These mutations might help the virus spread more easily or escape immune protection, although there’s no strong evidence of serious health risk so far.A435S,V445H ,T478I.The central government and health departments are monitoring the situation and reviewing public health measures.
India has recently identified two emerging COVID-19 subvariants—NB.1.8.1 and LF.7—according to data from the Indian SARS-CoV-2 Genomics Consortium (INSACOG). One case of NB.1.8.1 was detected in Tamil Nadu in April, while four cases of LF.7 were reported in Gujarat in May .
Both NB.1.8.1 and LF.7 are descendants of the JN.1 variant, which currently accounts for 53% of sequenced COVID-19 cases in India. BA.2 and other Omicron sublineages make up the remaining 47% .
The World Health Organization (WHO) has classified NB.1.8.1 and LF.7 as “Variants Under Monitoring” as of May 2025, indicating that they are being tracked for potential public health implications. Preliminary assessments suggest that NB.1.8.1 poses a low global health risk, although it carries mutations—such as A435S, V445H, and T478I—that may enhance transmissibility and immune evasion .
While the number of cases linked to these subvariants in India remains low, their emergence coincides with a gradual rise in COVID-19 infections in several states, including Kerala, Tamil Nadu, Maharashtra, and Karnataka . Health authorities are closely monitoring the situation and have conducted reviews to assess preparedness and response strategies.
Experts advise continued vigilance, including adherence to public health measures such as mask-wearing in crowded places, maintaining hand hygiene, and staying updated on vaccinations. Despite the current low risk assessment, ongoing surveillance and public cooperation are essential to manage and contain potential outbreaks effectively.
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